This study investigated the use of layer-specific fast strain-encoded cardiac magnetic resonance imaging (fSENC) for diagnosing and prognosticating acute myocardial injury in emergency department patients. It found that global longitudinal strain (GLS) and GLSdifference (the difference between epicardial and endocardial GLS) were effective predictors, with GLS showing a high diagnostic accuracy (AUC 91.8%) for myocardial injury. GLSdifference performed well in identifying non-ST-elevation myocardial infarction (NSTEMI) specifically (AUC 83.2%), and combining these measures with assessment of dysfunctional segments improved diagnostic performance further (AUC 87.5%). Incorporating fSENC into standard care enhanced overall diagnostic accuracy significantly (AUC 95.5%) compared to conventional methods alone. The study suggests that layer-specific strain analysis could serve as a valuable diagnostic tool for acute myocardial injuries, offering insights into prognosis and potentially guiding clinical management.
Cardiac Magnetic Resonance Imaging in Appraising Myocardial Strain and Biomechanics: A Current Overview
Subclinical alterations in myocardial structure and function occur early during the natural disease course. In contrast, clinically overt signs and symptoms occur during late phases, being associated with worse outcomes. Identification of such subclinical changes is critical for timely diagnosis and accurate management. Hence, implementing cost-effective imaging techniques with accuracy