Early Detection

When Precision Imaging Meets Preventive Cardiology

The heart is good at covering up problems. It finds ways to keep working even when it is damaged, so a person may feel fine and have normal test results for a long time. But underneath, the heart muscle may already be weakening. With the current standard test, the ejection fraction (EF), by the time a doctor spots the problem or a person starts feeling symptoms like shortness of breath, significant damage may have already occurred.1

MyoStrain®, using a technique called Fast-SENC, produces a MyoHealth® Score which is a single number showing how much of the heart muscle is working normally. Research has shown this can detect early, hidden heart problems in patients who feel fine and have normal standard test results, identifying people at risk of heart failure before serious damage occurs.2,3

  1. Packer M. J Am Coll Cardiol. 1992;20:248–254 and Sara JD, Toya T, Taher R, et al. European Cardiology Review. 2020;15:e13. (PMC7199190) 
  2. Korosoglou, et al. “Fast Strain-Encoded Cardiac Magnetic Resonance for Diagnostic Classification and Risk Stratification of Heart Failure Patients.” JACC: Cardiovascular Imaging. 2021. DOI: 10.1016/j.jcmg.2020.10.024 
  3. Hashemi et al. “CMR detects decreased myocardial deformation in asymptomatic patients at risk for heart failure.” Frontiers in Cardiovascular Medicine. 2023. (PMC9849678) 
How MyoHealth® Score Enables Early Detection

Quantifies Early Functional Changes

MyoHealth® Score quantifies segmental intramyocardial dysfunction across 48 segments, revealing early early heart muscle impairment.

Allows longitudinal monitoring

The MyoHealth® Score allows physicians to monitor disease progression, therapy and interventions response or lifestyle and traditional risk factors modification.

Chronic Disease Publications

April 5, 2021

Journal of Cardiovascular Magnetic Resonance

The study compared MyoStrain’s ability to quantify and differentiate asymptomatic patients based on their cardiac risk versus traditional ejection faction, reiterating the technology’s potential as a critical cardiac risk stratification tool enabling clinicians to identify at-risk patients early for individualized preventative treatment.

January 13, 2021

JACC Cardiovascular Imaging

This article demonstrates MyoStrain’s ability to identify patients with subclinical LV dysfunction and those at risk for heart failure-related outcomes compared with LVEF, providing an additional diagnostic window for prevention treatments.

August 8, 2019

Journal of Cardiovascular Magnetic Resonance

This abstract demonstrates the clinical application of MyoStrain as a tool to help quantify, monitor, and manage cardio-protection for oncology patients exhibiting cardiotoxicity.

Chronic Disease Publications