The study aimed to assess fast strain-encoded (SENC) cardiac magnetic resonance (CMR) and native T1 mapping in distinguishing between hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis. Ninety-nine patients (57 with HCM, 42 with amyloidosis) were analyzed for LV parameters, myocardial strain (global and segmental), and T1 values. HCM patients showed evenly distributed strain, while amyloidosis patients exhibited apical sparing with less impaired apical strain. T1 values were significantly higher in amyloidosis. The T1-to-basal segmental strain ratio effectively differentiated between conditions (Sensitivity = 85%, Specificity = 77%, AUC = 0.90), highlighting its potential in non-contrast CMR protocols for accurate diagnosis.
CMR detects decreased myocardial deformation in asymptomatic patients at risk for heart failure
A recently published article from Berlin highlights the potential of MyoStress in terms of identifying at-risk patients who have reserve and are therefore not symptomatic compared to patients with heart failure who have a preserved ejection fraction. This article shows that asymptomatic subjects with increased CV risk present with HFpEF