Stress Testing — Needle Free Ischemia Detection
Quantitative Precision for Coronary Artery Disease
Up to 20% of traditional stress tests produce false positives or false negatives leading to unnecessary procedures, delayed diagnosis, or missed ischemia.
MyoStress® is a rapid, and non-invasive breathing maneuver (BPV) stress test that quantifies how the heart responds to increased oxygen demand, helping clinicians detect myocardial ischemia and assess coronary artery disease (CAD) in 15 minutes, without pharmacologic stressors, contrast agents, or radiation exposure.
This allows physicians to visualize:
- Ischemic regions that fail to increase contraction during stress for guided individualized intervention.
- Viable, hibernating myocardium that recovers with medical therapy and
- Contractile reserve with improved MyoHealth® Score in non ischemic patients
Transforming Chest Pain Triage
Chest pain is one of the most common reasons people visit the emergency room, but finding out exactly what is causing it can be hard. Doctors often must run several tests one after another, which takes time and can still leave the cause unclear.
MyoStress® may change this by using a simple, needle-free breathing exercise that takes about 15 minutes. It helps doctors decide if a patient is having an immediate heart condition, send home patients whose chest pain is not from the heart, or direct patients with other heart problems to the right follow-up care.
- Santos Argueta AE, et al. Multivessel Coronary Artery Disease Presenting as a False-Negative Nuclear Stress Test. Cureus. 2024. PMC10923640 — directly states the 10–20% false negative figure for MPI.
- Ochs MM, Kajzar I, Salatzki J, Ochs AT, Riffel J, Osman N, Katus HA, Friedrich MG. Hyperventilation/Breath-Hold Maneuver to Detect Myocardial Ischemia by Strain-Encoded CMR: Diagnostic Accuracy of a Needle-Free Stress Protocol. JACC: Cardiovascular Imaging. 2021;14(10):1932–1944.
January 11, 2024
Cardiac magnetic resonance (CMR) is the gold standard for the diagnostic classification and risk stratification in most patients with cardiac disorders. The aim of the present study was to investigate the ability of Strain-encoded MR (SENC) for the prediction of major adverse cardiovascular events (MACE).
January 1, 2024
This study investigated the use of layer-specific fast strain-encoded cardiac magnetic resonance imaging (fSENC) for diagnosing and prognosticating acute myocardial injury in emergency department patients.
This study investigated the use of layer-specific fast strain-encoded cardiac magnetic resonance imaging (fSENC) for diagnosing and prognosticating acute myocardial injury in emergency department patients. It found that global longitudinal strain (GLS) and GLSdifference (the difference between epicardial and endocardial GLS) were effective predictors, with GLS showing a high diagnostic accuracy (AUC 91.8%) for myocardial injury. GLSdifference performed well in identifying non-ST-elevation myocardial infarction (NSTEMI) specifically (AUC 83.2%), and combining these measures with assessment of dysfunctional segments improved diagnostic performance further (AUC 87.5%). Incorporating fSENC into standard care enhanced overall diagnostic accuracy significantly (AUC 95.5%) compared to conventional methods alone. The study suggests that layer-specific strain analysis could serve as a valuable diagnostic tool for acute myocardial injuries, offering insights into prognosis and potentially guiding clinical management.
November 16, 2023
JACC Cardiovascular Imgaging
Several studies show a low (1-3%) but real risk of myocarditis in competitive athletes after SARS-CoV-2 infection.
November 17, 2021
Steen, H. et al.
September 6, 2011
Korosoglou, G. et al.
April 3, 2010
Korosoglou, G. et al.